The Briton is still in recovery after sustaining dreadful injuries in June when he hit a brick wall at high speed, fracturing ribs, a femur, and an elbow.
The five-times Tour de France winner was injured Sunday during a bike outing with friends and taken to hospital in Dendermonde, the paper added.
The Trek-Segafredo rider finished 16sec ahead of Alejandro Valverde and Tour de France champion Egan Bernal in the 243km race from Bergamo in northern Italy.
The 32-year-old Education First rider accelerated on the final kilometre on the steep climb up to Superga Basilica overlooking Turin, to finish in 4hr 03min 48sec.
The competitive spirit was boosted by the emergence of new teams like Qatar Army.
The league consists of seven races with the ever-popular finale held on Al Bidda Park’s “Red Road”.
The 23-year-old timed his last-gasp run to perfection to beat Italian Matteo Trentin and Swiss rider Stefan Kung.
The popular Welshman won the Tour in 2018 but came second behind his teammate, 21-year-old Egan Bernal in July.
The 34-year-old broke his neck, femur, elbow, hip and ribs when he crashed before stage four of the Criterium du Dauphine in France in June.
Groenewegen also took the first stage between Glasgow and Kirkcudbright.
The four-time Tour de France winner required surgery on Friday night to repair the tendon in his left thumb.
Jakobsen (Deceuninck-QuickStep) won a dramatic sprint to claim the narrowest of victories in El Puig, after Bennett had made an impressive recovery from taking a wrong turn around a roundabout.
Pozzovivo was involved in the collision while training near Cosenza in southern Italy.
Polish news website Onet reported Lambrecht collided with a concrete structure around 30 kilometres (19 miles) into the race after it suddenly began to rain.
Froome, who has seven Grand Tour victories to his name (two Vuelta and one Giro being the others), said all he was targetting was being alongside his team-mates at next year's Tour de France.